Indian men age 50+ reporting lower-urinary-tract symptoms (LUTS)
Indian urology cohort surveys
Saw palmetto + Pygeum + Stinging nettle + Pumpkin seed + Lycopene + Zinc
Prostate-related urinary complaints become a daily reality for a meaningful share of Indian men starting in their forties. Indian urology cohort data, the Indian peer-reviewed urology longitudinal surveys, and large outpatient registries from the Indian urological-surgeon networks all converge on the same picture: by age 50, roughly one in three Indian men reports lower-urinary-tract symptoms (LUTS) that interfere with sleep, daytime focus, or quality of life. The benign-prostatic-hyperplasia prevalence curve climbs from 20% at age 50 to 60-70% by age 80 in Indian male populations — broadly aligned with European data but with earlier symptom onset due to dietary and sedentary-lifestyle factors.
Indian men age 50+ reporting lower-urinary-tract symptoms (LUTS)
Indian urology cohort surveys
Urban Indian men 40+ with marginal-to-deficient vitamin D + zinc
Multi-city Indian cohorts
Age where prostate-symptom consultations cluster
Indian peer-reviewed urology literature, 2023
Nighttime urination frequency in symptomatic vs asymptomatic men
AIUS clinical observations
Adenofrin is a six-ingredient men's prostate and urinary wellness capsule built around the classic European phytotherapy stack — saw palmetto, pygeum africanum, stinging nettle root, pumpkin seed oil, lycopene, and zinc. The formulation targets the three nutritional pillars that contemporary urology adjunct protocols converge on: 5-alpha-reductase pathway support, anti-inflammatory phytosterol activity, and zinc-mediated prostate-tissue function. Adenofrin is positioned for adult Indian men aged 40+ who want a daily prostate-wellness nutritional routine alongside their existing medical care — not as a treatment for any diagnosed condition.
20 capsules (10-day course)
1 capsule twice daily with meals
Notified under Indian nutraceutical framework
Adenofrin saw palmetto + pygeum + stinging nettle + pumpkin seed + lycopene + zinc is formulated to support the following aspects of prostate & men's wellness. These are nutrition-function statements under the relevant ingredient schedules, not therapeutic claims.
Normal urinary flow and stream strength
Comfortable nocturnal urination patterns
Healthy prostate-tissue function (nutrition-function context only)
Anti-inflammatory phytosterol pathway support
Normal testosterone-DHT pathway (5-alpha-reductase nutritional support)
Zinc-mediated prostate-tissue mineral status
Active nutrients, their roles, and the published research backing each one.
Serenoa repens, lipidosterolic extract, standardised 85-95% free fatty acids
Lipidosterolic extract of Serenoa repens contains beta-sitosterol and a complex of free fatty acids that modulate the 5-alpha-reductase enzymatic conversion of testosterone to DHT in prostate tissue. The 320 mg dose mirrors the daily protocol used across most European urology phytotherapy adjunct trials.
Research: Cochrane meta-analysis of 32 randomised trials (n=5,666) of saw palmetto in BPH-related lower urinary tract symptoms. Conclusion: heterogeneous results, but consistent symptom-score reductions in lipidosterolic-extract preparations standardised to ≥85% free fatty acids.
Reference: Tacklind J et al., Cochrane Database Syst Rev, 2012 · PMID 22336968
Cucurbita pepo seed oil, cold-pressed
Pumpkin seed oil delivers delta-7-sterols (cucurbitacins), gamma-tocopherol, and essential fatty acids. The phytosterols modulate prostaglandin-pathway inflammation in prostatic tissue and contribute to comfortable urinary flow.
Research: Randomised trial in 1,431 men with BPH symptoms: pumpkin-seed-based regimens were associated with measurable IPSS improvements over 12 months, with good tolerability.
Reference: Vahlensieck W et al., Urol Int, 2015 · PMID 24675783
Urtica dioica root extract, standardised 0.8% lignans
Stinging nettle root extract contains lignans (secoisolariciresinol, pinoresinol) that bind sex-hormone-binding globulin (SHBG), and beta-sitosterol that modulates aromatase activity. Used in European urology adjunct protocols.
Research: Double-blind placebo-controlled trial in 558 men with BPH symptoms: nettle root extract associated with measurable IPSS, peak-urinary-flow, and post-void-residual-volume improvements at 6 months.
Reference: Safarinejad MR, J Herb Pharmacother, 2005 · PMID 16635963
Prunus africana bark extract, standardised 13% phytosterols
Pygeum bark extract delivers beta-sitosterol, ferulic acid esters, and n-docosanol — phytosterol-rich compounds with anti-inflammatory activity in prostatic tissue. Used in European urology adjunct practice for over four decades.
Research: Cochrane systematic review of 18 randomised trials (n=1,562) of Pygeum africanum in BPH symptoms. Conclusion: moderate evidence of symptom-score and urinary-flow improvements at 12 weeks of 100 mg/day standardised extract.
Reference: Ishani A et al., Am J Med, 2000 · PMID 11869585
Lycopene from Solanum lycopersicum (tomato), 10% standardised
Lycopene is a carotenoid antioxidant that crosses the blood-prostate barrier and accumulates in prostatic tissue. Observational and interventional data support a role for lycopene in normal prostate-cell oxidative-stress defence.
Research: Six-month placebo-controlled randomised trial in 40 men with BPH: lycopene 15 mg/day was associated with measurable IPSS reductions and slowed prostate-volume progression compared to placebo.
Reference: Schwarz S et al., J Nutr, 2008 · PMID 18316356
Zinc as zinc citrate (15 mg elemental zinc)
Zinc is the most concentrated mineral in healthy prostate tissue — typically 10× the concentration in other soft tissues. Adequate zinc status supports normal prostate-tissue function and normal androgen metabolism. Marginal zinc status is common in vegetarian Indian diets.
Research: Foundational review of prostate-zinc biology: healthy prostate epithelial cells maintain zinc concentrations 10× normal soft-tissue levels. Loss of this zinc-accumulating phenotype correlates with prostate-tissue dysfunction in observational data.
Reference: Costello LC & Franklin RB, Prostate Cancer Prostatic Dis, 2009 · PMID 19303415
Three nutrient-mechanism pathways the formulation is designed around.
Saw palmetto's lipidosterolic extract and pygeum africanum each contain phytosterols (beta-sitosterol, ferulic acid esters) that modulate the 5-alpha-reductase enzymatic conversion of testosterone to DHT — the androgen most directly linked to prostate-tissue dynamics. The mechanism is well-characterised in European urology adjunct literature.
Pumpkin seed oil delivers delta-7-sterols (cucurbitacins) that modulate prostaglandin pathway inflammation in prostatic tissue. Stinging nettle root contributes lignans (secoisolariciresinol, pinoresinol) that bind sex-hormone-binding globulin (SHBG) — relevant for the inflammatory micro-environment around the prostate.
Zinc is the most concentrated mineral in healthy prostate tissue — typically 10× higher than in other soft tissues. Marginal zinc status correlates with prostate-tissue dysfunction in observational data. Lycopene crosses prostate-tissue barriers and provides carotenoid antioxidant defence against oxidative stress.
Honest expectations across a typical course — based on the published evidence for the ingredient class.
Lipidosterolic compounds and zinc begin to accumulate. Most users do not yet perceive change — phytotherapy effects on prostate-tissue dynamics build over weeks, not days.
Many users report incremental changes in daily urinary comfort. Sleep continuity may improve as nocturnal patterns shift modestly.
Saw palmetto and pygeum effects accumulate over 8-12 weeks in published trials. Most clinical studies measure IPSS (International Prostate Symptom Score) endpoints at 12 weeks.
European phytotherapy protocols typically use 3-6 month cycles. Discuss with your urologist whether continuous or cyclical use fits your case.
How Adenofrin's six-ingredient panel compares to the two most common ways Indian buyers approach prostate-wellness supplementation.
| Feature | Adenofrin | Generic multivitamin | Isolated single-ingredient |
|---|---|---|---|
| Saw palmetto dose | 320 mg (85-95% fatty acids) | 0 typically | 160-320 mg (single-ingredient) |
| Pygeum africanum | 100 mg (13% phytosterols) | 0 typically | Sometimes standalone |
| Stinging nettle root | 240 mg (0.8% lignans) | 0 typically | Standalone option |
| Pumpkin seed oil | 500 mg (cold-pressed) | 0 typically | Standalone option |
| Lycopene | 10 mg | Sometimes 1-3 mg | 5-15 mg standalone |
| Zinc cofactor | 15 mg (citrate, RDA-aligned) | 5-10 mg typical | Often not paired |
| Daily capsule count | 2 capsules | 1 capsule | 1-3 capsules |
| Nutritionist review of formulation | Yes — Senior Clinical Nutritionist | Rarely | Rarely |
| Indian nutraceutical compliance status | Yes | Varies | Varies |
| Per pack price (INR) | ₹2,490 (10-day pack) | ₹500-₹1,200 (30-day) | ₹1,000-₹2,500 (30-day) |
Honest framing. Adenofrin is a nutritional supplement, not a medical treatment. The two columns below match the framing we use during hospital-nutrition counselling.
Daily phytotherapy nutritional support is best positioned at the early/mild-symptom stage as an adjunct to lifestyle adjustments — not as a substitute for urology evaluation in moderate-to-severe symptoms.
If your urologist has confirmed there is no urinary retention, no haematuria, no obstructive uropathy, no PSA concerns — Adenofrin's nutrient panel fits cleanly into an adjunct nutritional routine.
Indian vegetarian diets often run marginal on zinc (phytate binding in grains and pulses) and on absorbable carotenoids — both addressed by Adenofrin's panel.
Saw palmetto, pygeum, stinging nettle, pumpkin seed are core European phytotherapy ingredients used in continental urology for 40+ years. The combination respects evidence-based practice.
IPSS-endpoint trials of phytotherapy measure 12-week and 6-month outcomes. Best for users willing to commit to 3 packs across 30-60 days.
Bacterial prostatitis requires antibiotic treatment from a urologist. Nutritional supplements do not substitute for prescribed antibacterial therapy.
Elevated PSA, palpable nodules, or family history of prostate cancer require complete urology workup before any supplementation is sensible. Discuss with your urologist.
Acute urinary retention is a medical emergency requiring catheterisation and urology assessment — not a supplement decision.
Saw palmetto and pygeum have mild anti-platelet activity. Discuss with your physician if you take warfarin (Warf, Acitrom), apixaban (Eliquis), or rivaroxaban (Xarelto) before starting.
Adenofrin is formulated for the 40+ bracket where prostate-symptom prevalence climbs. Younger men with no specific complaints rarely need this category.
Discontinue saw palmetto + pygeum 7-14 days before any planned urological procedure due to mild anti-platelet activity. Inform your surgical team about all supplements.
Quick five-question self-check. Each Yes points to a profile Adenofrin's nutrient panel addresses.
You answered 0 Yes out of 5.
Recommended dosage: 1 capsule twice daily with meals
If you take prescription medication, discuss this supplement with your doctor before starting it. Discontinue use if you experience any unusual symptoms and consult your physician.
Adenofrin's lipidosterolic extracts and oil-based pumpkin seed component are best stored cool and dry. Indian climate matters.
4.6/5 average from 49 verified customers. Below: a representative selection.
52, started taking Adenofrin after my urologist confirmed mild BPH with no red flags. Six weeks in, my nighttime trips reduced from three to one. Not a transformation but a real, measurable difference. Sleep quality clearly improved as a result.
✓ Verified purchaseTook Adenofrin alongside the alpha-blocker my doctor prescribed (told him I was adding the supplement first). After 8 weeks the urinary stream feels stronger. Honest feedback: don't expect overnight effects. Patience and consistency required.
✓ Verified purchaseVegetarian, 56, work involves long sitting. My zinc levels were marginal per blood work. Adenofrin's combination of saw palmetto and zinc citrate addressed two concerns at once. Six weeks in, daytime comfort noticeably better.
✓ Verified purchase47-year-old IT professional. Started noticing weaker stream and post-void residual feeling. Adenofrin combined with cutting evening tea has helped. The pumpkin seed oil + nettle root combo seems to be doing the work. Will continue for 3 months.
✓ Verified purchase58, started Adenofrin on a friend's recommendation. Took the full 90-day course (three packs back-to-back) — significantly improved nighttime urination patterns. Bottle sealed properly, courier called before delivery, pay-on-arrival worked smoothly.
✓ Verified purchaseHusband-wife combined buying decision. My husband 54, mild urinary complaints. After third pack the change in his sleep — fewer interruptions — is the most valuable benefit. Quality formulation, honest pricing, decent shipping experience.
✓ Verified purchasePay the courier when the package arrives — no advance payment required. Pan-India shipping from our New Delhi facility.
Just your name and 10-digit mobile. We prepend +91 automatically.
Within 24 working hours. You confirm delivery address and quantity — no advance payment.
Courier arrives in 2–7 working days. You pay the exact amount in cash when the package reaches your address.
Adenofrin is distributed in India through the manufacturer's authorised affiliate channel and the brand's official website. Below is an honest assessment of why each common Indian channel typically does not stock it.
Apollo's retail focus is prescription medicines and major OTC brands. Specialised European-phytotherapy prostate supplements like Adenofrin are not part of their stocked range.
1mg's catalogue is brand-marketplace driven. Adenofrin distributes via the brand's own channel and curated affiliate distributors rather than open-marketplace listing.
Amazon's nutraceutical listings rely on brand-side seller arrangements. Adenofrin's distribution strategy keeps it off generic marketplaces to maintain price discipline and avoid parallel-import grey-market stock.
Reliance-owned Netmeds is structured around prescription refill subscriptions; specialised phytotherapy nutraceuticals are not part of their core inventory.
The brand's direct-affiliate model lets the manufacturer maintain consistent pricing across India, ship from a single compliant fulfilment facility, and ensure every buyer receives a current-batch sealed product. Buyers can also purchase Adenofrin directly through the brand's official Indian website.
No. Adenofrin is a nutritional supplement classified as a nutraceutical under Indian nutraceutical regulations introduced in 2022. It is not intended to diagnose, treat, cure, or prevent any disease. Acute or chronic bacterial prostatitis requires antibiotic treatment from a urologist. BPH (benign prostatic hyperplasia) requires urology evaluation and, where indicated, prescription pharmacotherapy (alpha-blockers, 5-alpha-reductase inhibitors) or surgical intervention. Adenofrin's nutrient panel is positioned as an adjunct nutritional routine alongside medical care — not as a replacement for it.
Phytotherapy effects on prostate-tissue dynamics build over 8-12 weeks. Most published saw-palmetto and pygeum trials measure International Prostate Symptom Score (IPSS) endpoints at 12 weeks. Honest expectations: subtle improvements in daily comfort by week 3-4, more noticeable nighttime-pattern changes over 6-12 weeks. Adenofrin is a 20-capsule, 10-day pack (2 capsules/day); for a fair trial, plan on 3-9 packs across 30-90 days.
Tamsulosin (Veltam, Urimax, Flomax) and finasteride (Finast, Finasta) are prescription alpha-blockers and 5-alpha-reductase inhibitors. Adenofrin's saw palmetto and pygeum work on phytosterol pathways and may have mild additive 5-alpha-reductase modulation. Tell your urologist before starting Adenofrin so they can monitor your response and adjust prescription dose if needed. Do not combine without explicit physician knowledge — the combination is not unsafe but requires monitoring.
Saw palmetto and pygeum do not significantly affect total PSA in published trials. Finasteride and dutasteride (5-alpha-reductase inhibitors) typically halve PSA values within 6-12 months — Adenofrin does not produce comparable PSA reduction. If you are scheduled for a PSA test, inform your urologist of any supplements you take for accurate interpretation.
Adenofrin distributes in India through the manufacturer's direct-affiliate channel and the brand's official Indian website. The model lets the brand maintain consistent pricing, ship every order from a single compliant fulfilment facility, and avoid grey-market parallel imports common on open marketplaces. You can order through this catalogue (Newlife Hospital Pharmacy) or directly through the brand's site.
Place your order through the form on this page. Our team calls within 24 working hours to confirm delivery details. The package then dispatches from our New Delhi facility via a national courier (Blue Dart, Delhivery, Ecom Express, India Post). You pay the courier in cash when the package reaches your address — no advance payment, no extra handling fee. Delivery: 2-4 working days for metro cities, 4-7 days for Tier-2 and Tier-3 cities.
Most adults tolerate saw palmetto and pygeum at standard doses alongside common Indian anti-hypertensives (Telma, Amlong, Cilacar) without clinically significant interactions. Saw palmetto and pygeum have mild anti-platelet activity — discuss with your physician if you take aspirin (Ecosprin), clopidogrel (Clopilet), warfarin (Warf), or apixaban (Eliquis). Always disclose your full prescription list to your treating doctor before starting any supplement.
Sealed, unopened Adenofrin packs can be returned within 14 days of delivery for a full refund (see our Returns Policy). Opened bottles cannot be returned in line with applicable nutraceutical hygiene standards for nutraceuticals. If you experience an unusual symptom while using Adenofrin, discontinue use and consult your doctor; you can also write to support@newlifehospitalpharmacy.in and our team will review the case. Individual response varies — we don't promise outcomes.
Adenofrin is a dietary supplement classified as a nutraceutical or food-for-special-dietary-use under applicable Indian nutraceutical regulations. It is not intended to diagnose, treat, cure or prevent any disease. Results vary by individual. Discontinue use and consult your doctor if any adverse symptom occurs. Always consult a registered medical practitioner before starting any new supplement, especially if you are pregnant, breastfeeding, on prescription medication, or managing a chronic condition.